Skip to product information
  • A bottle of True Botanicals Microbiome Enzyme Essence in an amber brown glass bottle with a black cap, set against a clean off-white background.
  • A large smooth beige circular swatch centered on a white background, with small black text below reading, 'A prebiotic essence to protect, balance, and strengthen the microbiome.'.
  • A promotional graphic for a skincare product featuring a close-up of a woman's face and hand on the right, with text on the left reading '90% said their skin looks dewy after using this product' and '86% said their skin feels baby soft'. The top reads 'MICROBIOME ENZYME ESSENCE'.
  • A close-up portrait of a woman with natural skin texture and makeup, showing her face from the shoulders up against a plain light background.
  • A close-up botanical ingredient graphic with text overlays reading 'Microbiome Enzyme Essence' and 'Intelligent Ingredients,' listing pineapple & papaya enzyme, wild-sourced finger lime, and buckwheat ferment.
  • A beige promotional graphic with the headline 'Key Benefits for Targeted Results' and bullet points about diminishing fine lines and wrinkles, restoring firmness and elasticity, and even skin tone. The design uses warm beige tones with glossy liquid droplet illustrations and the brand name 'Microbiome Enzyme Essence' at the bottom.
  • A beige product information card with the headline 'Safe for people and the planet.' and text listing hypoallergenic, vegan, dermatologist-tested, and 100% non-toxic.
  • Pregnant woman wearing a beige ribbed one-shoulder top and blue jeans, smiling against a light gray background with text about Sorette third-party certification and a Sorette Approved for Motherhood seal.
  • A bottle of True Botanicals Microbiome Enzyme Essence in an amber brown glass bottle with a black cap, set against a clean off-white background.
  • A large smooth beige circular swatch centered on a white background, with small black text below reading, 'A prebiotic essence to protect, balance, and strengthen the microbiome.'.
  • A promotional graphic for a skincare product featuring a close-up of a woman's face and hand on the right, with text on the left reading '90% said their skin looks dewy after using this product' and '86% said their skin feels baby soft'. The top reads 'MICROBIOME ENZYME ESSENCE'.
  • A close-up portrait of a woman with natural skin texture and makeup, showing her face from the shoulders up against a plain light background.
  • A close-up botanical ingredient graphic with text overlays reading 'Microbiome Enzyme Essence' and 'Intelligent Ingredients,' listing pineapple & papaya enzyme, wild-sourced finger lime, and buckwheat ferment.
  • A beige promotional graphic with the headline 'Key Benefits for Targeted Results' and bullet points about diminishing fine lines and wrinkles, restoring firmness and elasticity, and even skin tone. The design uses warm beige tones with glossy liquid droplet illustrations and the brand name 'Microbiome Enzyme Essence' at the bottom.
  • A beige product information card with the headline 'Safe for people and the planet.' and text listing hypoallergenic, vegan, dermatologist-tested, and 100% non-toxic.
  • Pregnant woman wearing a beige ribbed one-shoulder top and blue jeans, smiling against a light gray background with text about Sorette third-party certification and a Sorette Approved for Motherhood seal.

    Microbiome Enzyme Essence

    $82
    Size  
    Full Size (4oz | 118mL)
    • 20% off your first 3 orders
    • 15% off every order after
    • Product samples on first 2 orders
    • Cancel anytime
    Frequency Recommendation
    We recommend the following replenishment cycle:
    • Usage
    • Frequency
    • Twice a day
    • Every 2 months
    • Once a day
    • Every 3 months
    • Just a few times a week
    • Every 4 months
    Free Shipping on Orders $45+
    Try risk-free for 30 days or your money back

    Description

    Clinically proven to deliver plump, dewy-looking skin, this next-generation essence is your skin’s daily prebiotic. Bioactive fruit enzymes gently resurface, while protecting, balancing, and strengthening the microbiome—like gut health, but for your skin.

    How to Use

    After cleansing, pour 2-3 shakes in the palms of hands and gently press and pat into face and neck. Use in the morning and in the evening as needed.

    Ingredient List

    camellia sinensis (green tea) leaf extract*, zingiber officinale (ginger) water*, aloe barbadensis leaf juice*, glycerin, maltodextrin, phenethyl alcohol, bromelain, papain, xanthan gum, ethylhexylglycerin, citrus australasica (finger lime) fruit extract, davidsonia jerseyana (davidson plum) fruit extract, sodium hyaluronate, sodium phytate, citric acid, water/aqua/eau, sodium benzoate, potassium sorbate.

    Dermatologist Recommended

    "Cellular turnover is vital for youthful-looking skin, but it slows with age. This essence is exceptional because its micro-exfoliators promote cell turnover without disrupting the skin’s microbiome."

    Dr. Daniel Butler, MD, Board-Certified Dermatologist

    Real Results from our Community

    All images are taken by our community after 30 days of use and are not retouched or modified in any way.

      Clinical Results

      93%
      said their skin is healthier-looking*
      90%
      said their skin looks dewy after using this product*
      86%
      said their skin feels baby soft*

      *Based on a 28-day clinical study of 35 women aged 25-65, twice daily use

      Intelligent Ingredients

      We pioneer plant intelligence with precision. Our clinically proven formulas are developed with potent botanical actives that speak your skin's own language: sourced from nature; safe for people and the planet.

      Our Pineapple & Papaya Enzymes work to soften and naturally exfoliate by shedding the dead skin layer on the surface of the skin.
      Rich in AHAs (Alpha Hydroxy Acids), Finger Lime helps to break down dead skin cells and shed the outermost layer of dry skin, allowing the epidermis to increase absorption of water and emollients.
      Our Buckwheat Ferment is a fermented prebiotic that helps to balance, support and nourish the skin's microbiome.

      FAQs

      Is this good for all skin types?

      Yes, all skin types can benefit from the Microbiome Enzyme Essence, especially dry skin types. It’s also great for sensitive skin types!

      Is this product safe to use during pregnancy?

      Yes! Our Microbiome Enzyme Essence is MADE SAFE® Certified, which ensures it is free from over 15,000+ known toxins and has undergone further rigorous testing to ensure it does not contain any ingredients known to or suspected of harming pregnant individuals. For more information, check the MADE SAFE® Healthy Pregnancy Guide.

      We are also proud that this product has earned the Sorette Seal of Approval. That means the formulation has been vetted against Sorette’s No-Go List™, which restricts or prohibits ingredients connected to reproductive, developmental, or endocrine toxicity. The Seal indicates full ingredient disclosure and formulation transparency.

      If you are pregnant or breastfeeding, we always recommend consulting with your doctor before introducing any new skincare products into your routine. Everyone's skin and situation is different, so we cannot take into account your unique needs that may contribute to differentiated standards during your pregnancy or postpartum period.

      How long will the Microbiome Enzyme Essence last?

      Each bottle contains approximately 236 uses. When used twice daily, it will last about 118 days. If used once a day, it will last double the time - 236 days. Your usage may vary depending on how much you apply.

      Beyond the Bottle

      Environmental Impact