• Phyto-Retinol Sleep Serum
  • Phyto-Retinol Sleep Serum
  • Phyto-Retinol Sleep Serum benefits highlighted on a warm, radiant background, emphasizing its retinol-like effects without irritation, including smoothing, brightening, and firming the skin.
  • An amber glass bottle of True Botanicals Phyto-Retinol Sleep Serum with a gold and black pump dispenser rests on a reflective golden surface with scattered droplets. Bold text highlights clinical results, showing 100% saw fewer fine lines and wrinkles, 97% experienced transformation without irritation, and 94% noticed brighter, more radiant skin. A disclaimer notes results are from a six-week study of 33 women aged 35–65.
  • In a six-week single-blind study involving 33 women aged 35-65, 100% of participants using Phyto-Retinol Sleep Serum saw a noticeable reduction in fine lines and wrinkles. This serum, applied nightly, delivers visible anti-aging results with a gentler alternative to traditional retinol.
  • An amber glass bottle of True Botanicals Phyto-Retinol Sleep Serum with a gold and black pump dispenser is displayed in the center. Surrounding the bottle are botanical ingredients, including a red powder representing astaxanthin on the left and yellow primrose flowers on the right. Text at the top highlights Peptilium®, described as a clinically proven phyto-retinol ingredient that works twice as fast as traditional retinol without sensitizing side effects.
  • Before-and-after comparison showcasing the results of using Phyto-Retinol Sleep Serum on the neck area. The "Before" image shows visible fine lines and sagging, while the "After 6 Weeks" image illustrates smoother, firmer skin with a reduction in lines. The accompanying text reads: "REDUCTION IN fine lines & wrinkles, softens & smooths skin, firms sagging skin."
  • In a six-week single-blind study of 33 women aged 35-65, 91% reported their skin felt firmer after using Phyto-Retinol Sleep Serum. Participants applied the serum once nightly, and results highlighted its ability to improve skin firmness while offering a gentle alternative to traditional retinol products.
  • Phyto-Retinol Sleep Serum | Clinically proven 2X faster & better than traditional retinol
  • Phyto-Retinol Sleep Serum
  • Phyto-Retinol Sleep Serum
  • Phyto-Retinol Sleep Serum benefits highlighted on a warm, radiant background, emphasizing its retinol-like effects without irritation, including smoothing, brightening, and firming the skin.
  • An amber glass bottle of True Botanicals Phyto-Retinol Sleep Serum with a gold and black pump dispenser rests on a reflective golden surface with scattered droplets. Bold text highlights clinical results, showing 100% saw fewer fine lines and wrinkles, 97% experienced transformation without irritation, and 94% noticed brighter, more radiant skin. A disclaimer notes results are from a six-week study of 33 women aged 35–65.
  • In a six-week single-blind study involving 33 women aged 35-65, 100% of participants using Phyto-Retinol Sleep Serum saw a noticeable reduction in fine lines and wrinkles. This serum, applied nightly, delivers visible anti-aging results with a gentler alternative to traditional retinol.
  • An amber glass bottle of True Botanicals Phyto-Retinol Sleep Serum with a gold and black pump dispenser is displayed in the center. Surrounding the bottle are botanical ingredients, including a red powder representing astaxanthin on the left and yellow primrose flowers on the right. Text at the top highlights Peptilium®, described as a clinically proven phyto-retinol ingredient that works twice as fast as traditional retinol without sensitizing side effects.
  • Before-and-after comparison showcasing the results of using Phyto-Retinol Sleep Serum on the neck area. The "Before" image shows visible fine lines and sagging, while the "After 6 Weeks" image illustrates smoother, firmer skin with a reduction in lines. The accompanying text reads: "REDUCTION IN fine lines & wrinkles, softens & smooths skin, firms sagging skin."
  • In a six-week single-blind study of 33 women aged 35-65, 91% reported their skin felt firmer after using Phyto-Retinol Sleep Serum. Participants applied the serum once nightly, and results highlighted its ability to improve skin firmness while offering a gentle alternative to traditional retinol products.
  • Phyto-Retinol Sleep Serum | Clinically proven 2X faster & better than traditional retinol

Phyto-Retinol Sleep Serum

$90

A smarter way to retinol. Phyto-Retinol Serum is powered by Peptilium®—a breakthrough ingredient clinically proven to work 2X faster and better than traditional retinol.

Full Size (1oz | 30mL)
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Frequency Recommendation
We recommend the following replenishment cycle:
  • Usage
  • Frequency
  • Twice a day
  • Every 1 month
  • Once a day
  • Every 2 months
  • Just a few times a week
  • Every 4 months
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What It Is

Traditional synthetic retinol may often wreak havoc on the skin due to its skin-sensitizing effects that may cause irritation, redness, extreme dryness, or peeling. But when it comes to delivering clinical-level anti-aging results, your skin shouldn't have to feel any pain. Phyto-Retinol Serum is a luxurious, hydrating, age-defying serum powered by Peptilium®, a potent, cutting-edge biopeptide that’s clinically proven to work 2X faster and better than traditional synthetic retinol—without any sensitization, irritation, or dryness.

In clinical testing, this first-ever formula activated by Peptilium®—a rich antioxidant sustainably sourced from cranberry pulp—delivers 10 visible anti-aging benefits, including improved hydration, brightness, firmness, elasticity, smoothness, improved evenness of skin tone, and a reduction in the look of fine lines, wrinkles, and pores.

This award-winning serum is dermatologist-tested, hypoallergenic, microbiome-friendly, pregnancy-safe, and MADE SAFE® certified.

Key Ingredients
  • Primrose is celebrated for its soothing and nourishing properties, helping to maintain skin's elasticity and hydration while promoting a balanced, radiant complexion.

    Primrose

  • Peptilium Ingredient

    Peptilium®

  • Astaxanthin, nature's most powerful antioxidant, works to combat free radicals, enhance skin elasticity, and promote a youthful, radiant glow.

    Astaxanthin

    Full Ingredients List

    camellia sinensis (green tea) leaf extract*, aloe barbadensis leaf juice*, glycerin, hydrogenated soybean oil, hydrogenated jojoba oil, hydrogenated lecithin, phenethyl alcohol, hippophae rhamnoides fruit oil*, coriandrum sativum (coriander) seed oil, mauritia flexuosa fruit oil*, rosa rubiginosa seed oil*, salvia hispanica seed oil*, sclerotium gum, avena sativa (oat) bran extract, algin, water, persea gratissima (avocado) oil, ethylhexylglycerin, sodium phytate, citrus aurantium dulcis (orange) peel extract, citric acid, amyris balsamifera bark oil, canarium luzonicum gum oil, citrus limon (lemon) leaf oil, lavandula hybrida oil, rosa damascena flower oil, rosmarinus officinalis (rosemary) leaf oil, tocopherol, vaccinium macrocarpon (cranberry) fruit extract, astaxanthin*, 1,2-hexanediol, caprylyl glycol, primula veris flower extract, citraᵻ, citronellol, geraniol, limonene, linalool.

    *Organic

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      FAQs

      Can I use this product with my Chebula Serum, Vitamin C and/or other exfoliants?

      Our Phyto-Retinol Sleep Serum is microbiome-friendly and non-irritating, meaning it can be paired, and used with Vitamin C, exfoliants and other skincare products that one typically needs to avoid when using traditional retinol. We recommend using Chebula Serum in the morning, and Phyto-Retinol Sleep Serum in the evening.

      Can I use this product every day if it’s so powerful?

      Yes, you can use this every day. While traditional retinol is known to disrupt the skin barrier - which is what leads to redness and dryness - Peptillium® is clinically proven to significantly improve skin barrier function, so you can use this every day without sensitizing side effects.

      How does this compare to the Phyto-Retinol Vitamin A Booster?

      We recommend using both. Phyto-Retinol Sleep Serum should be used in the evening for targeting immediate skin aging concerns with Peptilium®, a phyto-retinol ingredient that is clinically proven to work 2X faster and better than traditional retinol. Phyto-Retinol Vitamin A Booster should be used in the morning to promote long-term skin barrier health and resilience with high concentrations of Provitamin A ingredients, Omega-Fatty Acids and Antioxidants.

      Is this product safe to use during pregnancy?

      Yes! Our Phyto-Retinol Sleep Serum is MADE SAFE® Certified, which ensures it is free from over 15,000 known toxins and has undergone further rigorous testing to ensure it does not contain any ingredients known to or suspected of harming pregnant individuals. If you are pregnant or breastfeeding, we always recommend consulting with your doctor before introducing any new skincare products into your routine. Everyone's skin and situation is different, so we cannot take into account your unique needs that may contribute to differentiated standards during your pregnancy or postpartum period. For more information, check the MADE SAFE® Healthy Pregnancy Guide. 

      How long will the Phyto-Retinol Sleep Serum last?

      Each bottle contains approximately 120 uses. When used once daily, it will last about 120 days (or 4 months). Your usage may vary depending on how much you apply, but just a few drops deliver powerful results while being gentle on your skin.

      Pure. Potent. Proven.®

      Pure. Potent. Proven.®

      Luxurious, aromatherapeutic products formulated with the purest, functional plant actives that fill your skin's nutrient gaps, support your skin's microbiome, and deliver clinically proven results. This is a better path to anti-aging.

      Luxurious, aromatherapeutic products formulated with the purest, functional plant actives that fill your skin's nutrient gaps, support your skin's microbiome, and deliver clinically proven results. This is a better path to anti-aging.

      Made Safe logo
      PETA Approved logo
      EWG Verified
      Microbiome Friendly
      Learn More